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Fun Sharing:The Story Between Ice Crystals and Frozen Foods (Part 3)

Our sincere suggestion—how to improve the quality of food affected by ice crystals

 

Choose frozen food

 It is internationally recognized that when the central temperature of frozen food reaches -18℃ rapidly and is stably refrigerated at this low temperature, the original color, flavor and quality of the food can be maximally preserved.

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There are definitely many people who hold the bias that frozen meat is not as good as fresh meat. There are always people who insist on getting up early to select the freshest meat from the market and then store it in the fridge after they can’t finish it. Did you ever think that this fresh meat, from the slaughter in the early morning until it reaches your hands at 7 or 8 o'clock, has been exposed to the environment for a long time, and a large number of microorganisms have multiplied. Moreover, the leftover fresh meat has to be put in the fridge, which has a freezing effect that cannot match professional equipment, causing further quality degradation. In this case, why not choose frozen meat from a reliable source from the beginning and thaw as much as you need to eat? Now the development of frozen equipment in China is already very mature, and the production of frozen food has increased substantially. In the near future, with further improvement of freezing/refrigeration technology, the gap between frozen food and fresh food will be negligible.

 

How to thaw

 

From the perspective of thawing, it can also alleviate the damage caused by ice crystals to some extent. The most common methods, also used in daily life, include natural thawing, water thawing (cold water/hot water), and microwave thawing. Researchers have conducted experiments investigating the effects of these thawing methods on the status and nutritional value of frozen vegetables, meat, and other foods. These studies reveal that each method has its own set of advantages and disadvantages, making it crucial to do structure confirmation and choose an appropriate method to achieve optimal results. Here are various methods that have practical significance, providing a helpful reference for practical use.

 

Air thawing

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Using air as the thawing medium, also known as natural thawing. This thawing method has low cost and easy operation, and is suitable for large-volume meat; however, the thawing rate is slow, the meat surface is prone to discoloration, there is a certain degree of juice loss, and it will also be contaminated by dust and breed a large number of microorganisms. It is recommended to put the food to be thawed in the lower temperature in a cold storage room the day before (cold storage thawing), which can reduce the loss of juice and inhibit the growth of microorganisms. This slow thawing method is very suitable for frozen meat, mantou, bread, etc. If the situation is urgent, the frozen meat can also be placed in two-layer aluminum trays for thawing, which enhances heat transfer and achieves rapid thawing.

 

Water thawing


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With water as the defrosting medium, the defrosting rate is faster than air defrosting. But remember not to use hot water to defrost ingredients! In this case, the food loses a lot of juice and the quality is greatly reduced. So water thawing must be used in cold water, and pork and other meat products should not be immersed directly in water as far as possible, it is best to bring the packaging to reduce microbial reproduction. However, for frozen seafood such as shrimp, eel, and tuna, soaking in still water is insufficient. Recent research shows that using this method leads to a more uniform crystallization development, lower juice loss, and smaller impact on muscle fiber tissue, optimizing the retention of frozen fish and shrimp's freshness and nutrition. Additionally, adding a little salt to the water decreases the water's freezing point, resulting in a faster thawing time without affecting the meat's freshness.


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(eg. The effect of different thawing methods on tuna tissue structure: a: air thawing, fish tissue is exposed to air for a longer time, leading to the proliferation of microorganisms, decomposing tissue proteins, thus losing its original denseness and presenting a larger gap; b: hydrostatic thawing, the best effect; c: running water thawing, the ice crystals in direct contact with the water flow melt first, thawing faster, the melted liquid phase water to (d: microwave thawing, tuna muscle fiber gap is the largest, connective tissue destruction is more serious, this is because the microwave heating directly to the fish, the highest temperature, so that the protein is destroyed to a greater extent.)


Microwave defrosting


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The microwave acts directly on the inside of the food, causing the molecules inside the food to collide with each other and thaw by frictional heat generation, and the surface of the food does not come into contact with the electrode, thus avoiding microbial contamination. However, there are still controversial studies on its effect on the quality of frozen food, which is commonly associated with problems such as external heat and internal cold, and uneven thawing. In the use of this method, be sure to pay attention to the microwave frequency (not more than about 700 W low-power gear, now commercially available microwave ovens will also set a special defrosting gear), thawed objects are not too thick, the surface covered with plastic wrap, immediately take immediately thawed immediately cooking. Fish and shrimp try not to use microwave defrosting, frozen fruit is still quite suitable. A large number of studies have shown that frozen strawberries, mangoes, corn, etc. put into a low-power microwave oven for a few minutes can be thawed quickly, and can maintain a greater degree of quality.


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(eg. It was found that microwave thawing of corn took the least time, lost the least juice, retained the best structure, and had the highest total sugar content.)


Text above: Effect of different thawing methods on frozen corn, thawing in room temperature water bath, thawing in air, thawing in boiling water bath, thawing in microwave, juice loss rate, hardness, total sugar content.


Ultrasonic thawing


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Without having to think about money, perhaps a small ultrasound machine can be acquired at home? Because in the current research, ultrasonic thawing is considered one of the best reputation among the commonly used thawing methods. Ultrasonic action on water produces thermal effect, mechanical effect and cavitation effect, on the one hand, the cavitation effect assists the thermal effect to make the heat more smoothly conducted to the food interior, on the other hand, the mechanical effect can effectively destroy the ice crystals within the food, thus accelerating the thawing to achieve the purpose of fast and stable thawing of food.


Conclusion


Of course there are more high-tech defrosting methods, as well as different defrosting methods in conjunction with the method, here is not one by one, after all, our purpose is also to be able to quickly eat a plate of thawed food taste no different from the fresh dish, too much tedious steps some of the cart before the horse, and the above knowledge is enough for daily life. So, go look at the frozen dishes in the refrigerator again, your defrosting ideas clear?

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Amorphous Solid Dispersion (Spray Drying & Hot-melt Extrusion) Dr. LianFeng Huang Joins Crystal Pharmatech as Chief Scientist Characterization and Evaluation of Amorphous Solid Dispersion (ASD) - Part 1 Characterization and Evaluation of Amorphous Solid Dispersion-Part 2 Parameter Sensitivity with GastroPlus Critical Quality Attribute D0 Impact in ADC Modality SAPA Annual Conference (Gold Corporate Sponsorship) Crystal Bio Solutions Bio Analytics API Form and Solid-State Research Crystallization Development Mini-tablet Knowledge Hub Molecules-to-Medicine: Accelerating Drug Development through Collaboration PBPK in Preclinical/FIH Scenarios Whitepaper Case Study 4: Gatifloxacin - Crystalline Form Changes With A Licensed Compound Amorphous Solid Dispersions Using Thermodynamic Phase Maps in API Crystallization Process Design Pre-clinical Formulation Strategies Sponsored by Crystal Pharmatech Date: 2:00-3:00 pm EDT, Wednesday, Whatch on-demand
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Crystallization Development Services Excipient Selection and Compatibility Studies Analytical Chemistry ASD Series Unlock Solubility Enhancement Methods for Poorly Soluble Oral Drugs Development and Production Application Cases of Amorphous Solid Dispersion Formulations (II) - Spray Drying Overcoming Poor Solubility and Dissolution of Insoluble Molecules Patent Analysis of Resmetirom Sterility Assays in Drug/Device Manufacturing 2024 CASSS - Mass Spec Symposium Flow Cytometry About Us Pre-formulation Studies Formulations for PK/Efficacy/Tox Studies Crystallization and Spray Drying Process Development, Scale-Up, and Technology Transfer Case Study 6: Oxybutynin- Crystalline Change From Salt to Free Base Learn about Drug Eutectic Screening Crystal Pharmatech's CDMO Business Unit - Crystal Formulation Services Received China Drug Product Manufacturing License, Achieving the Important Milestone in Formulation Capability Development and Production Application Cases of Amorphous Solid Dispersion Formulations (I) - Hot Melt Extrusion Review of Polymorph Patent Application of 30 Small Molecule New Drugs Approved by the FDA in 2023 Biologics ChemOutsourcing 2024 Crystal Bio Webinar ELISpot Assays Solid-State NMR Analysis Resources Avoiding Drug Failures: Right First Time; Fast First Time Exploring the Pharmaceutical Solid State by Molecular Simulation Crystallization Process Method SMART Development of Pre-clinical Candidates Crystal Pharmatech Recognized as "Best Partner" by Allorion Therapeutics for Excellent Services Formulation and Analytical Development Animal Dosing Vehicle Selection Detecting Low-Level Crystallinity in ASD-like Samples Using ssNMR Techniques Understand ASD Manufacturing Strategies, Choose the Optimal One Immuno-Oncology Summit 2024 - Meet Crystal Bio at Booth 15 Molecular Biology Clinical and Commercial Manufacturing Amorphous Solid Dispersions Careers Tools and Strategies for De-risking Rapid Drug Substance and Drug Product Development API Crystallization Crystal Pharmatech Returned to AAPS 2022 PharmSci 360 Fun Sharing: The Secret Behind the Silky Smoothness of Chocolate (Part 2) GMP Manufacturing A Brief Introdction to Amorphous Solid Dispersion Technology Amorphous Solid Dispersions: Two Heads Are Better Than One FIH-PMF-FMF Manufacturing The Bioprocessing Summit 2024 - Meet Crystal Bio at Booth T13 Contact Us Crystal Pharmatech and Particle Sciences Form a US-China Pharmaceutical CRO Partnership Advancements in Analytical Tools for API and DP Characterization Co-crystals Fun Sharing: The Secret behind the Silky Smooth Enjoyment of Chocolate (Part 3) Unlock Solubility Enhancement Methods for Poorly Soluble Oral Drugs Meet Crystal Pharmatech at 2024 Controlled & Modified Drug Release Summit Assessment of Powder Segregation in Direct Compression (DC) Blends: Developing Predictive and PAT Tools Search Result Webinar Series Crystal Pharmatech Raises $10 Million to Accelerate Growth Solid Forms: The Good; The Bad; The Ugly Impact of Solid-state in Early Development Fun Sharing: The Secret Behind the Silkiness of Chocolate (Part 1) Join Crystal Pharmatech for the Sino-American Pharmaceutical Professionals Association (SAPA) NE 26th Annual Conference Formulation Design and Development of Fixed Dose Combination Solid Oral Dosage Forms Sitemap Crystal Formulation Services, Formulation Tailor-made for Your Molecules Utility of Single Crystal in Form and Formulation Selection Optimal Preclinical Formulation Development ​Crystal Pharmatech will be in San Diego from June 3-6 at BIO International Convention Drug Delivery and Patient Centric Approaches to Drug Development  404 Candoo Enables the Successful Development of a BCS 4 Combo Drug Product Introduction to MicroED Technology and Solutions Salts Fun Sharing:The Story Between Ice Crystals and Frozen Foods (Part 3) Meet Crystal Pharmatech at Chinese Antibody Society 2024 Annual Conference Privacy Policy International Company Crystal Pharmatech Finds CCIT An Optimal Spot for First US Location Formulation Implications Pharmaceutical Solid-state Forms Meet Crystal Pharmatech at 15th Drug Discovery Strategic Summit (DDSS) Submission Successful! Crystal Pharmatech Triples Headquarters in Biobay, China, with More Floors and Labs Fun Sharing: The Relationship Between Ice Crystals and Frozen Foods (Part 1) Clinical Supply Meet Crystal Pharmatech at Sorption Symposium North America 2024 Taggg Xceleron and Crystal Pharmatech Announce Partnership to Improve Early Clinical Development Utilizing Absolute Bioavailability Trials and Solid-State Solutions CPHI North America - Meet Crystal Pharmatech at Booth 1441 Search Result Service Crystal Pharmatech Introduces Customized Service Packages for Customers Seeking Materials Science Approaches in Drug Discovery and Development Fun Sharing: The Story of Ice Crystals and Frozen Foods (Part 2) Meet Crystal Pharmatech at MIDD+ Boston 2024 Search Result Others Crystal Pharmatech Expands Leadership Team Case Study on Development and Production Applications of Amorphous Solid Dispersions - Hot Melt Extrusion Formulation Development: Fastest-to-FIH Without Sacrificing Quality Crystal Formulation Services(CFS)Opens New Formulation Development Center and Analytical R&D Lab in Suzhou, China event page Development and Production Application Case Study of Amorphous Solid Dispersions: Spray Drying DCAT WEEK: CMC Discussions Amorphous Solid Dispersion Technology and the Service Advantages of Crystal Pharmaceutical AAPS PharmSci360 - Meet Us at Booth # 2106 Candoo's Formulation Technology Platform Featured in the Drug Development & Delivery Journal ASD Column | Mastering Stable Art: Unveiling Key Factors Influencing Physical Stability of Amorphous Solid Dispersions Meet the Crystal Pharmatech formulation team next week at CPHI Crystal Pharmatech and the Future of Pharma at AAPS PharmSci 360 Crystal Formulation Services' GMP Manufacturing Facility Successfully Passes the Remote Audit by US Client, Marking a Key Milestone for Its International Expansion ASD Column | How to Select Polymers in Hot-melt Extrusion Process? Crystal Pharmatech Raring to Go to ChemOutsourcing 2022 ASD Column | Understanding the ASD Preparation Methods and Selecting the Optimal Method for Solution Crystal Bio Welcomes Dr. Shiaw-Lin (Billy) Wu as Co-Founder and Chief Scientific Officer CPHI North america - Meet Us at Booth #530 Polymorphs, Solvatomorphs and Hydrate of Dabrafenib Crystal Bio Appoints Dr. Ye Gu as Co-founder, CTO, and Head of USA BD Shining Glory: Unveiling the "True Eye" behind the Veil of Drug Crystal Forms Crystal Pharmatech's CDMO Business Unit - Crystal Formulations Services Successfully Passed EU QP Audit Applications of Dynamic Moisture Adsorption in Crystal Research Meet Crystal Pharmatech at AAPS National Biotechnology Conference Application of Granularity Analysis in Crystal Typing Research Assessment of CQA in mRNA-LNP Modality DCAT Week 2025 A Brief Introduction to Amorphous Solid Dispersion Technology ADME Simulations: Insights into Bioavailability and Pharmacokinetics Understand ASD Manufacturing Strategies, Choose the Optimal One Parameter Sensitivity with GastroPlus Review of Polymorph Patent Application of 30 Small Molecule New Drugs Approved by the FDA in 2023 Unveil Key Factors Influencing the Physical Stability of Amorphous Solid Dispersions Characterization and Evaluation of Amorphous Solid Dispersion (ASD) - Part 1 Optimizing Polymer Selection for Amorphous Solid Dispersion in Hot Melt Extrusion Processes
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