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In-Silico PBPK Modeling and Simulation

After completing molecule's basic benchwork and characterization, it is time to leverage powerful simulation software for in vitro-in vivo extrapolation.


Integrating in silico advancements into program will help consumer expedite timeline for CMC (chemistry, manufacturing, and controls) and dosing strategies. We can identify absorption risks in the early development and optimize preclinical and clinical dosing strategies.

 

Crystal pharmatech offers PBPK modeling and simulation consulting services using GastroPlus® software – the pharmaceutical industry's most sophisticated platform for the prediction of drug absorption and disposition in human and animal species. We can extrapolate in silico predictions for:


Shortening your clinical development timeline with in silico FIH dose selection and formulation optimization is possible and can improve the following:

Resources of In-Silico PBPK Modeling and Simulation

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Contact Us
bd_global@crystalpharmatech.com +1-609-604-8303
U.S
Suite 500-B, 3000 Eastpark Blvd, Cranbury, New Jersey 08512, USA
Canada
6800 Kitimat Rd, Unit 1, Mississauga, Ontario, Canada L5N 5M1
China
No. 288, Jiangyun Road, Suzhou Industrial Park, Suzhou, China, 215123
Suite 500-B, 3000 Eastpark Blvd, Cranbury, New Jersey 08512, USA
bd_global@crystalpharmatech.com +1-609-604-8303